Collagen cross-links scale with passive stiffness in dystrophic mouse muscles, but are not altered with administration of a lysyl oxidase inhibitor

In Duchenne muscular dystrophy (DMD), a lack of functional dystrophin leads to myofiber instability and progressive muscle damage that results in fibrosis. While fibrosis is primarily characterized by an accumulation of extracellular matrix (ECM) components, there are changes in ECM architecture dur...

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Detalles Bibliográficos
Autores principales: Brashear, Sarah E., Wohlgemuth, Ross P., Hu, Lin-Ya, Jbeily, Elias H., Christiansen, Blaine A., Smith, Lucas R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9612445/
https://www.ncbi.nlm.nih.gov/pubmed/36302059
http://dx.doi.org/10.1371/journal.pone.0271776

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9612445/
https://www.ncbi.nlm.nih.gov/pubmed/36302059
http://dx.doi.org/10.1371/journal.pone.0271776

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