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Annona muricata L. peel extract inhibits carbohydrate metabolizing enzymes and reduces pancreatic β-cells, inflammation, and apoptosis via upregulation of PI3K/AKT genes

BACKGROUND AND OBJECTIVE: Annona muricata L. peel has been recognized for many ethnobotanical uses, including diabetes management. However, limited detailed scientific information about its mechanism of antidiabetic activity exists. The objective of this study was to evaluate the anti-diabetic prope...

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Detalles Bibliográficos
Autores principales: Ojo, Oluwafemi Adeleke, Grant, Susan, Amanze, Jennifer Chidubem, Oni, Abosede Itunuoluwa, Ojo, Adebola Busola, Elebiyo, Tobiloba Christiana, Obafemi, Tajudeen Olabisi, Ayokunle, Damilare Iyinkristi, Ogunlakin, Akingbolabo Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9612462/
https://www.ncbi.nlm.nih.gov/pubmed/36301972
http://dx.doi.org/10.1371/journal.pone.0276984