In-silico Investigations of quinine and quinidine as potential Inhibitors of AKR1B1 and AKR1B10: Functional and structural characterization

The aberrant expression of aldo keto reductases (AKR1B1 & AKR1B10) has been extensively studied in different types of cancer especially the colon cancer but a very few studies have yet been reported regarding the discovery of inhibitors for the treatment of colon cancer by targeting these isozym...

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Detalles Bibliográficos
Autores principales: Ejaz, Syeda Abida, Saeed, Amna, Birmani, Pervez Rashid, Katubi, Khadijah Mohammedsalaeh, Elqahtani, Zainab Mufarreh, Al-Buriahi, M. S., Ujan, Rabail, Siddique, Farhan, Ahmed, Samia ben, Alrowaili, Z. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9612481/
https://www.ncbi.nlm.nih.gov/pubmed/36301939
http://dx.doi.org/10.1371/journal.pone.0271602

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9612481/
https://www.ncbi.nlm.nih.gov/pubmed/36301939
http://dx.doi.org/10.1371/journal.pone.0271602

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