Delivery of Antibody-Like Molecules, Monobodies, Capable of Binding with SARS-CoV-2 Virus Nucleocapsid Protein, into Target Cells

Based on previous studies, two antibody-like molecules, monobodies, capable of high-affinity interaction with the SARS-CoV-2 nucleocapsid protein (dissociation constant of tens of nM) were selected. For delivery to target cells, genetically engineered constructs containing monobody and TAT peptide,...

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Detalles Bibliográficos
Autores principales: Khramtsov, Y. V., Ulasov, A. V., Lupanova, T. N., Georgiev, G. P., Sobolev, A. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pleiades Publishing 2022
Materias:
Biochemistry, Biophysics, and Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9612593/
https://www.ncbi.nlm.nih.gov/pubmed/36303056
http://dx.doi.org/10.1134/S1607672922050088

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9612593/
https://www.ncbi.nlm.nih.gov/pubmed/36303056
http://dx.doi.org/10.1134/S1607672922050088

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