Cargando…
Stability and expression of SARS-CoV-2 spike-protein mutations
Protein fold stability likely plays a role in SARS-CoV-2 S-protein evolution, together with ACE2 binding and antibody evasion. While few thermodynamic stability data are available for S-protein mutants, many systematic experimental data exist for their expression. In this paper, we explore whether s...
Autores principales: | Bæk, Kristoffer T., Mehra, Rukmankesh, Kepp, Kasper P. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9612610/ https://www.ncbi.nlm.nih.gov/pubmed/36302994 http://dx.doi.org/10.1007/s11010-022-04588-w |
Ejemplares similares
-
Structural heterogeneity and precision of implications drawn from cryo-electron microscopy structures: SARS-CoV-2 spike-protein mutations as a test case
por: Mehra, Rukmankesh, et al.
Publicado: (2022) -
Modelling SARS-CoV-2 spike-protein mutation effects on ACE2 binding
por: Thakur, Shivani, et al.
Publicado: (2023) -
Molecular dynamics derived life times of active substrate binding poses explain K(M) of laccase mutants
por: Mehra, Rukmankesh, et al.
Publicado: (2018) -
A structural-chemical explanation of fungal laccase activity
por: Mehra, Rukmankesh, et al.
Publicado: (2018) -
Side-by-side comparison of Notch- and C83 binding to γ-secretase in a complete membrane model at physiological temperature
por: Dehury, Budheswar, et al.
Publicado: (2020)