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Sox17 Deficiency Promotes Pulmonary Arterial Hypertension via HGF/c-Met Signaling
In large-scale genomic studies, Sox17, an endothelial-specific transcription factor, has been suggested as a putative causal gene of pulmonary arterial hypertension (PAH); however, its role and molecular mechanisms remain to be elucidated. We investigated the functional impacts and acting mechanisms...
Autores principales: | , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9612711/ https://www.ncbi.nlm.nih.gov/pubmed/36205124 http://dx.doi.org/10.1161/CIRCRESAHA.122.320845 |