Sox17 Deficiency Promotes Pulmonary Arterial Hypertension via HGF/c-Met Signaling

In large-scale genomic studies, Sox17, an endothelial-specific transcription factor, has been suggested as a putative causal gene of pulmonary arterial hypertension (PAH); however, its role and molecular mechanisms remain to be elucidated. We investigated the functional impacts and acting mechanisms...

Descripción completa

Detalles Bibliográficos
Autores principales: Park, Chan Soon, Kim, Soo Hyun, Yang, Hae Young, Kim, Ju-Hee, Schermuly, Ralph Theo, Cho, Ye Seul, Kang, Hyejeong, Park, Jae-Hyeong, Lee, Eunhyeong, Park, HyeonJin, Yang, Jee Myung, Noh, Tae Wook, Lee, Seung-Pyo, Bae, Sun Sik, Han, Jinju, Ju, Young Seok, Park, Jun-Bean, Kim, Injune
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9612711/
https://www.ncbi.nlm.nih.gov/pubmed/36205124
http://dx.doi.org/10.1161/CIRCRESAHA.122.320845

Ejemplares similares

Ejemplares similares