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Kinetic and data-driven modeling of pancreatic β-cell central carbon metabolism and insulin secretion
Pancreatic β-cells respond to increased extracellular glucose levels by initiating a metabolic shift. That change in metabolism is part of the process of glucose-stimulated insulin secretion and is of particular interest in the context of diabetes. However, we do not fully understand how the coordin...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9612825/ https://www.ncbi.nlm.nih.gov/pubmed/36251711 http://dx.doi.org/10.1371/journal.pcbi.1010555 |