Lipopolysaccharide distinctively alters human microglia transcriptomes to resemble microglia from Alzheimer's disease mouse models

Alzheimer's disease (AD) is the most common form of dementia, and risk-influencing genetics implicates microglia and neuroimmunity in the pathogenesis of AD. Induced pluripotent stem cell (iPSC)-derived microglia (iPSC-microglia) are increasingly used as a model of AD, but the relevance of hist...

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Detalles Bibliográficos
Autores principales: Monzón-Sandoval, Jimena, Burlacu, Elena, Agarwal, Devika, Handel, Adam E., Wei, Liting, Davis, John, Cowley, Sally A., Cader, M. Zameel, Webber, Caleb
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9612871/
https://www.ncbi.nlm.nih.gov/pubmed/36254682
http://dx.doi.org/10.1242/dmm.049349

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9612871/
https://www.ncbi.nlm.nih.gov/pubmed/36254682
http://dx.doi.org/10.1242/dmm.049349

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