Regulation of Nodal signaling propagation by receptor interactions and positive feedback

During vertebrate embryogenesis, the germ layers are patterned by secreted Nodal signals. In the classical model, Nodals elicit signaling by binding to a complex comprising Type I/II Activin receptors (Acvr) and the co-receptor Tdgf1. However, it is currently unclear whether receptor binding can als...

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Detalles Bibliográficos
Autores principales: Preiß, Hannes, Kögler, Anna C, Mörsdorf, David, Čapek, Daniel, Soh, Gary H, Rogers, Katherine W, Morales-Navarrete, Hernán, Almuedo-Castillo, María, Müller, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9612913/
https://www.ncbi.nlm.nih.gov/pubmed/36149406
http://dx.doi.org/10.7554/eLife.66397

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9612913/
https://www.ncbi.nlm.nih.gov/pubmed/36149406
http://dx.doi.org/10.7554/eLife.66397

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