Tumor elimination by clustered microRNAs miR-306 and miR-79 via noncanonical activation of JNK signaling

JNK signaling plays a critical role in both tumor promotion and tumor suppression. Here, we identified clustered microRNAs (miRNAs) miR-306 and miR-79 as novel tumor-suppressor miRNAs that specifically eliminate JNK-activated tumors in Drosophila. While showing only a slight effect on normal tissue...

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Detalles Bibliográficos
Autores principales: Wang, Zhaowei, Xia, Xiaoling, Li, Jiaqi, Igaki, Tatsushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9612915/
https://www.ncbi.nlm.nih.gov/pubmed/36222503
http://dx.doi.org/10.7554/eLife.77340

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9612915/
https://www.ncbi.nlm.nih.gov/pubmed/36222503
http://dx.doi.org/10.7554/eLife.77340

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