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Effects of human tissue acoustic properties, abdominal wall shape, and respiratory motion on ultrasound-mediated hyperthermia for targeted drug delivery to pancreatic tumors

BACKGROUND: PanDox is a Phase-1 trial of chemotherapeutic drug delivery to pancreatic tumors using ultrasound-mediated hyperthermia to release doxorubicin from thermally sensitive liposomes. This report describes trial-related hyperthermia simulations featuring: (i) new ultrasonic properties of huma...

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Detalles Bibliográficos
Autores principales: Gray, Michael, Spiers, Laura, Coussios, Constantin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9612938/
https://www.ncbi.nlm.nih.gov/pubmed/35853611
http://dx.doi.org/10.1080/02656736.2022.2091799