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Systems biology analyses reveal enhanced chronic morphine distortion of gut-brain interrelationships in simian human immunodeficiency virus infected rhesus macaques

BACKGROUND: Commonly used opioids, such as morphine have been implicated in augmented SIV/HIV persistence within the central nervous system (CNS). However, the extent of myeloid cell polarization and viral persistence in different brain regions remains unclear. Additionally, the additive effects of...

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Detalles Bibliográficos
Autores principales: Olwenyi, Omalla A., Johnson, Samuel D., Bidokhti, Mehdi, Thakur, Vandana, Pandey, Kabita, Thurman, Michellie, Acharya, Arpan, Uppada, Srijayaprakash, Callen, Shannon, Giavedoni, Luis, Ranga, Udaykumar, Buch, Shilpa J., Byrareddy, Siddappa N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9613112/
https://www.ncbi.nlm.nih.gov/pubmed/36312033
http://dx.doi.org/10.3389/fnins.2022.1001544