Gain-of-function TLR7 and loss-of-function A20 gene variants identify a novel pathway for Mendelian lupus and lupus nephritis

Systemic lupus erythematosus (SLE) is a chronic and inflammatory autoimmune disease of unknown origin that may cause kidney disease, i.e. lupus nephritis (LN). Within a wider trend towards an expanding field of genetic causes of kidney disease, two recent reports have emphasized the role of Mendelia...

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Detalles Bibliográficos
Autores principales: Villalvazo, Priscila, Carriazo, Sol, Rojas-Rivera, Jorge, Ramos, Adrián M, Ortiz, Alberto, Perez-Gomez, Maria Vanessa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Editorial Comment
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9613427/
https://www.ncbi.nlm.nih.gov/pubmed/36324999
http://dx.doi.org/10.1093/ckj/sfac152

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9613427/
https://www.ncbi.nlm.nih.gov/pubmed/36324999
http://dx.doi.org/10.1093/ckj/sfac152

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