WNK3 kinase maintains neuronal excitability by reducing inwardly rectifying K(+) conductance in layer V pyramidal neurons of mouse medial prefrontal cortex

The with-no-lysine (WNK) family of serine-threonine kinases and its downstream kinases of STE20/SPS1-related proline/alanine-rich kinase (SPAK) and oxidative stress-responsive kinase-1 (OSR1) may regulate intracellular Cl(−) homeostasis through phosphorylation of cation-Cl(−) co-transporters. WNK3 i...

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Detalles Bibliográficos
Autores principales: Sinha, Adya Saran, Wang, Tianying, Watanabe, Miho, Hosoi, Yasushi, Sohara, Eisei, Akita, Tenpei, Uchida, Shinichi, Fukuda, Atsuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Molecular Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9613442/
https://www.ncbi.nlm.nih.gov/pubmed/36311015
http://dx.doi.org/10.3389/fnmol.2022.856262

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9613442/
https://www.ncbi.nlm.nih.gov/pubmed/36311015
http://dx.doi.org/10.3389/fnmol.2022.856262

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