Cargando…

Inhibition of autophagy with chloroquine dysregulates mitochondrial quality control and energetics in adipocytes

Autophagy is a complex degradation pathway through which damaged or dysfunctional proteins and organelles are removed. Its pharmacological modulators have been extensively used in a wide range of basic research and preclinical studies. However, the effects of these inhibitors on metabolism, in addit...

Descripción completa

Detalles Bibliográficos
Autores principales: Javaid, Hafiz Muhammad Ahmad, Lim, Hwayeon, Shin, Sooim, Huh, Joo Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pharmaceutical Society of Korea 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9613452/
https://www.ncbi.nlm.nih.gov/pubmed/36306017
http://dx.doi.org/10.1007/s12272-022-01412-3