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METTL3 mediates chemoresistance by enhancing AML homing and engraftment via ITGA4
Chemoresistant leukemia relapse is one of the most common causes of death for acute myeloid leukemia (AML) patients and the homing/engraftment in bone marrow (BM) are crucial steps for AML cells to acquire chemoresistance by interacting with stromal cell components. No crosstalk between m(6)A modifi...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9613467/ https://www.ncbi.nlm.nih.gov/pubmed/36266324 http://dx.doi.org/10.1038/s41375-022-01696-w |