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METTL3 mediates chemoresistance by enhancing AML homing and engraftment via ITGA4

Chemoresistant leukemia relapse is one of the most common causes of death for acute myeloid leukemia (AML) patients and the homing/engraftment in bone marrow (BM) are crucial steps for AML cells to acquire chemoresistance by interacting with stromal cell components. No crosstalk between m(6)A modifi...

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Detalles Bibliográficos
Autores principales: Li, Mingying, Ye, Jingjing, Xia, Yuan, Li, Meng, Li, Guosheng, Hu, Xiang, Su, Xiuhua, Wang, Dongmei, Zhao, Xin, Lu, Fei, Li, Jingxin, Ma, Daoxin, Sun, Tao, Ji, Chunyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9613467/
https://www.ncbi.nlm.nih.gov/pubmed/36266324
http://dx.doi.org/10.1038/s41375-022-01696-w