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新型Ⅰ类和Ⅱb类选择性HDAC抑制剂甲磺酸普依司他治疗弥漫大B细胞淋巴瘤的体外药效学和作用机制研究

OBJECTIVE: To investigate the in vitro inhibitory activity of a novel class Ⅰ and Ⅱb selective histone deacetylase(HDAC)inhibitor, purinostat mesylate(PM), in diffuse large B-cell lymphoma and its mechanism. METHODS: The 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide method was used t...

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Detalles Bibliográficos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Editorial office of Chinese Journal of Hematology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9613491/
https://www.ncbi.nlm.nih.gov/pubmed/36709169
http://dx.doi.org/10.3760/cma.j.issn.0253-2727.2022.09.007