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Direct cell-to-cell transfer in stressed tumor microenvironment aggravates tumorigenic or metastatic potential in pancreatic cancer

Pancreatic cancer exhibits a characteristic tumor microenvironment (TME) due to enhanced fibrosis and hypoxia and is particularly resistant to conventional chemotherapy. However, the molecular mechanisms underlying TME-associated treatment resistance in pancreatic cancer are not fully understood. He...

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Detalles Bibliográficos
Autores principales: Jang, Giyong, Oh, Jaeik, Jun, Eunsung, Lee, Jieun, Kwon, Jee Young, Kim, Jaesang, Lee, Sang-Hyuk, Kim, Song Cheol, Cho, Sung-Yup, Lee, Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9613679/
https://www.ncbi.nlm.nih.gov/pubmed/36302783
http://dx.doi.org/10.1038/s41525-022-00333-w