Cargando…

Direct cell-to-cell transfer in stressed tumor microenvironment aggravates tumorigenic or metastatic potential in pancreatic cancer

Pancreatic cancer exhibits a characteristic tumor microenvironment (TME) due to enhanced fibrosis and hypoxia and is particularly resistant to conventional chemotherapy. However, the molecular mechanisms underlying TME-associated treatment resistance in pancreatic cancer are not fully understood. He...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jang, Giyong, Oh, Jaeik, Jun, Eunsung, Lee, Jieun, Kwon, Jee Young, Kim, Jaesang, Lee, Sang-Hyuk, Kim, Song Cheol, Cho, Sung-Yup, Lee, Charles
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9613679/ https://www.ncbi.nlm.nih.gov/pubmed/36302783 http://dx.doi.org/10.1038/s41525-022-00333-w

Ejemplares similares

Genome‐scale CRISPR screening identifies cell cycle and protein ubiquitination processes as druggable targets for erlotinib‐resistant lung cancer
por: Lee, Jieun, et al.
Publicado: (2020)

Augmentation of the RNA m6A reader signature is associated with poor survival by enhancing cell proliferation and EMT across cancer types
por: Oh, Jaeik, et al.
Publicado: (2022)

Phenotypic Plasticity Conferred by the Metastatic Microenvironment of the Brain Strengthens the Intracranial Tumorigenicity of Lung Tumor Cells
por: Wei, Xu-Ge, et al.
Publicado: (2021)

Shed syndecan-2 enhances tumorigenic activities of colon cancer cells
por: Choi, Sojoong, et al.
Publicado: (2015)

Hyperglycemia aggravates microenvironment hypoxia and promotes the metastatic ability of pancreatic cancer
por: Li, Wei, et al.
Publicado: (2018)

iCSDB: an integrated database of CRISPR screens
por: Choi, Ahyoung, et al.
Publicado: (2020)

TRRAP stimulates the tumorigenic potential of ovarian cancer stem cells
por: Kang, Kyung Taek, et al.
Publicado: (2018)

Effects of Cell Density and Microenvironment on Stem Cell Mitochondria Transfer among Human Adipose-Derived Stem Cells and HEK293 Tumorigenic Cells
por: Burch, Shalise A., et al.
Publicado: (2022)

Inflammatory conversion of quiescent osteoblasts by metastatic breast cancer cells through pERK1/2 aggravates cancer-induced bone destruction
por: Back, Jungho, et al.
Publicado: (2021)

Novel HER3/MUC4 oncogenic signaling aggravates the tumorigenic phenotypes of pancreatic cancer cells
por: Lakshmanan, Imayavaramban, et al.
Publicado: (2015)

Rapamycin Response in Tumorigenic and Non-Tumorigenic Hepatic Cell Lines
por: Jimenez, Rosa H., et al.
Publicado: (2009)

Systemic Injection of Oncolytic Vaccinia Virus Suppresses Primary Tumor Growth and Lung Metastasis in Metastatic Renal Cell Carcinoma by Remodeling Tumor Microenvironment
por: Park, Jee Soo, et al.
Publicado: (2022)

Characterization of circulating breast cancer cells with tumorigenic and metastatic capacity
por: Koch, Claudia, et al.
Publicado: (2020)

KPT6566 induces apoptotic cell death and suppresses the tumorigenicity of testicular germ cell tumors
por: Sun, Ruijing, et al.
Publicado: (2023)

Extracellular histones aggravate autoimmune arthritis by lytic cell death
por: Jung, Jaeyong, et al.
Publicado: (2022)

Tumorigenic Cell Reprogramming and Cancer Plasticity: Interplay between Signaling, Microenvironment, and Epigenetics
por: Poli, Vittoria, et al.
Publicado: (2018)

Embryonic stem cell preconditioned microenvironment suppresses tumorigenic properties in breast cancer
por: He, Ningning, et al.
Publicado: (2016)

Upregulation of adenylate cyclase 3 (ADCY3) increases the tumorigenic potential of cells by activating the CREB pathway
por: Hong, Seung-Hyun, et al.
Publicado: (2013)

Embryonic Stem Cells Are Redirected to Non-Tumorigenic Epithelial Cell Fate by Interaction with the Mammary Microenvironment
por: Boulanger, Corinne A., et al.
Publicado: (2013)

Antitumor Effect of Metformin in Combination with Binimetinib on Melanoma Cells
por: Lee, Eunsung, et al.
Publicado: (2021)

A physical sciences network characterization of non-tumorigenic and metastatic cells
Publicado: (2013)

Anti-inflammatory and Anti-tumorigenic Effects of Açai Berry in Helicobacter felis-infected mice
por: Lee, Ju Yup, et al.
Publicado: (2016)

Downregulation of ADAMTS3 Suppresses Stemness and Tumorigenicity in Glioma Stem Cell
por: Kim, Hyun‐Jin, et al.
Publicado: (2022)

Role of cancer stem cell-associated inflammation in creating pro-inflammatory tumorigenic microenvironments
por: Jinushi, Masahisa
Publicado: (2014)

Carcinoma-Associated Mesenchymal Stem/Stromal Cells: Architects of the Pro-tumorigenic Tumor Microenvironment
por: Frisbie, Len, et al.
Publicado: (2022)

Letter to the Editor: Commentary on Does the COVID-19 Screening Test Affect the Postoperative Prognosis of Patients Who Undergo Emergency Surgery for Cerebral Hemorrhage? (Korean J Neurotrauma 2022;18:198–207)
por: Yun, Giyong, et al.
Publicado: (2023)

Potential Pro-Tumorigenic Effect of Bisphenol A in Breast Cancer via Altering the Tumor Microenvironment
por: Kwon, Youngjoo
Publicado: (2022)

Cyclosporin A Aggravates Calcification of Vascular Smooth Muscle Cells Under High-Glucose Conditions with a Calcifying Medium
por: Kim, Dae Hee, et al.
Publicado: (2018)

Mammosphere culture of metastatic breast cancer cells enriches for tumorigenic breast cancer cells
por: Grimshaw, Matthew J, et al.
Publicado: (2008)

Sensitive Tumorigenic Potential Evaluation of Adult Human Multipotent Neural Cells Immortalized by hTERT Gene Transduction
por: Lee, Kee Hang, et al.
Publicado: (2016)

Scaffold-Free Coculture Spheroids of Human Colonic Adenocarcinoma Cells and Normal Colonic Fibroblasts Promote Tumorigenicity in Nude Mice()()()
por: Park, Jong-il, et al.
Publicado: (2016)

Dual Relationship Between Stromal Cells and Immune Cells in the Tumor Microenvironment
por: Mun, Jeong-Yeon, et al.
Publicado: (2022)

Tumorigenicity Evaluation of Umbilical Cord Blood-derived Mesenchymal Stem Cells
por: Park, Sang-Jin, et al.
Publicado: (2016)

Aggravation of Acute Ischemic Stroke with Cerebral Hypoperfusion after Intravenous Propacetamol
por: Kim, Sang Yeon, et al.
Publicado: (2021)

Differences in Tumor Immune Microenvironment in Metastatic Sites of Breast Cancer
por: Lee, Hyunjong, et al.
Publicado: (2021)

Hematopoietic Stem Cell–Derived Cancer–Associated Fibroblasts Are Novel Contributors to the Pro-Tumorigenic Microenvironment()()
por: McDonald, Lindsay T., et al.
Publicado: (2015)

Tumor-initiating stem cell shapes its microenvironment into an immunosuppressive barrier and pro-tumorigenic niche
por: He, Xi, et al.
Publicado: (2021)

Single-cell RNA reveals a tumorigenic microenvironment in the interface zone of human breast tumors
por: Yang, Wei, et al.
Publicado: (2023)

High tumor hexokinase-2 expression promotes a pro-tumorigenic immune microenvironment by modulating CD8+/regulatory T-cell infiltration
por: Kim, Sehui, et al.
Publicado: (2022)

Mitoribosomal defects aggravate liver cancer via aberrant glycolytic flux and T cell exhaustion
por: Song, Byong-Sop, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_1m6p2pbqkt44tm8j8fkep7u0ub