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Subclinical diagnosis of cisplatin-induced ototoxicity with biomarkers

A mouse model with cisplatin-induced ototoxicity was used in addition to human samples from the ITMAT Biobank at the University of Pennsylvania. Mouse auditory brainstem responses (ABR), inner ear histology, perilymph cisplatin sampling, and measurement of serum prestin via ELISA were performed. Hum...

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Detalles Bibliográficos
Autores principales: Generotti, Charles, Cox, Brandon C., Singh, Jarnail, Hamilton, Deborah, McKenzie, Erica, O’Malley, Bert W., Li, Daqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9613680/
https://www.ncbi.nlm.nih.gov/pubmed/36302835
http://dx.doi.org/10.1038/s41598-022-23034-x