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Subclinical diagnosis of cisplatin-induced ototoxicity with biomarkers
A mouse model with cisplatin-induced ototoxicity was used in addition to human samples from the ITMAT Biobank at the University of Pennsylvania. Mouse auditory brainstem responses (ABR), inner ear histology, perilymph cisplatin sampling, and measurement of serum prestin via ELISA were performed. Hum...
Autores principales: | Generotti, Charles, Cox, Brandon C., Singh, Jarnail, Hamilton, Deborah, McKenzie, Erica, O’Malley, Bert W., Li, Daqing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9613680/ https://www.ncbi.nlm.nih.gov/pubmed/36302835 http://dx.doi.org/10.1038/s41598-022-23034-x |
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