Senescent neutrophils-derived exosomal piRNA-17560 promotes chemoresistance and EMT of breast cancer via FTO-mediated m6A demethylation

Cellular senescence is characterized by a tumor-suppressive program as well as a pro-inflammatory secretome. Neutrophils constitute significant compositions of malignancies and play key roles in tumor development. However, the role of senescent neutrophils in cancer progression is presently unexplor...

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Detalles Bibliográficos
Autores principales: Ou, Baochi, Liu, Yuan, Gao, Zongxuan, Xu, Jun, Yan, Yunwen, Li, Yongxiang, Zhang, Jingjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9613690/
https://www.ncbi.nlm.nih.gov/pubmed/36302751
http://dx.doi.org/10.1038/s41419-022-05317-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9613690/
https://www.ncbi.nlm.nih.gov/pubmed/36302751
http://dx.doi.org/10.1038/s41419-022-05317-3

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