Human mtRF1 terminates COX1 translation and its ablation induces mitochondrial ribosome-associated quality control

Translation termination requires release factors that read a STOP codon in the decoding center and subsequently facilitate the hydrolysis of the nascent peptide chain from the peptidyl tRNA within the ribosome. In human mitochondria eleven open reading frames terminate in the standard UAA or UAG STO...

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Detalles Bibliográficos
Autores principales: Nadler, Franziska, Lavdovskaia, Elena, Krempler, Angelique, Cruz-Zaragoza, Luis Daniel, Dennerlein, Sven, Richter-Dennerlein, Ricarda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9613700/
https://www.ncbi.nlm.nih.gov/pubmed/36302763
http://dx.doi.org/10.1038/s41467-022-34088-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9613700/
https://www.ncbi.nlm.nih.gov/pubmed/36302763
http://dx.doi.org/10.1038/s41467-022-34088-w

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