Relating individual cell division events to single-cell ERK and Akt activity time courses

Biochemical correlates of stochastic single-cell fates have been elusive, even for the well-studied mammalian cell cycle. We monitored single-cell dynamics of the ERK and Akt pathways, critical cell cycle progression hubs and anti-cancer drug targets, and paired them to division events in the same s...

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Detalles Bibliográficos
Autores principales: Stern, Alan D., Smith, Gregory R., Santos, Luis C., Sarmah, Deepraj, Zhang, Xiang, Lu, Xiaoming, Iuricich, Federico, Pandey, Gaurav, Iyengar, Ravi, Birtwistle, Marc R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9613772/
https://www.ncbi.nlm.nih.gov/pubmed/36302844
http://dx.doi.org/10.1038/s41598-022-23071-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9613772/
https://www.ncbi.nlm.nih.gov/pubmed/36302844
http://dx.doi.org/10.1038/s41598-022-23071-6

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