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On the intrinsic nature of viral pathogenesis: The assumption of a Darwinian paradigm to describe COVID-19 pandemic

Our hypothesis about evolution of the COVID-19 pandemic foresees an inverse relation between infectivity (R0) and lethality (L) of SARS-CoV-2. The above parameters are driven by a continuing mutation process granting the virus a clear survival advantage over virulence. For interpreting this relation...

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Detalles Bibliográficos
Autores principales: Roggero, Pier Francesco, Calistri, Arianna, Palù, Giorgio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9613777/
https://www.ncbi.nlm.nih.gov/pubmed/36320938
http://dx.doi.org/10.1016/j.csbj.2022.10.037