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Insights on attenuating autophagy cellular and molecular pathways versus methotrexate-induced toxicity via liposomal turmeric therapy

BACKGROUND: Methotrexate (MX), a competitive inhibitor of dihydrofolate reductase, can inhibit DNA and RNA production and is a powerful anticancer agent widely utilized in clinical practice for treating nonneoplastic maladies, as psoriasis and rheumatoid arthritis; meanwhile, its probable prescripti...

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Detalles Bibliográficos
Autores principales: Kadry, Mai O., Ammar, Naglaa M., Hassan, Heba A., Abdel Megeed, Rehab M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9613829/
https://www.ncbi.nlm.nih.gov/pubmed/36301384
http://dx.doi.org/10.1186/s43141-022-00430-4