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Ubiquitin proteolysis of a CDK-related kinase regulates titan cell formation and virulence in the fungal pathogen Cryptococcus neoformans

Fungal pathogens often undergo morphological switches, including cell size changes, to adapt to the host environment and cause disease. The pathogenic yeast Cryptococcus neoformans forms so-called ‘titan cells’ during infection. Titan cells are large, polyploid, display alterations in cell wall and...

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Detalles Bibliográficos
Autores principales: Cao, Chengjun, Wang, Keyi, Wang, Yina, Liu, Tong-Bao, Rivera, Amariliz, Xue, Chaoyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9613880/
https://www.ncbi.nlm.nih.gov/pubmed/36302775
http://dx.doi.org/10.1038/s41467-022-34151-6