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Mitochondria supply sub-lethal signals for cytokine secretion and DNA-damage in H. pylori infection

The bacterium Helicobacter pylori induces gastric inflammation and predisposes to cancer. H. pylori-infected epithelial cells secrete cytokines and chemokines and undergo DNA-damage. We show that the host cell’s mitochondrial apoptosis system contributes to cytokine secretion and DNA-damage in the a...

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Detalles Bibliográficos
Autores principales: Dörflinger, Benedikt, Badr, Mohamed Tarek, Haimovici, Aladin, Fischer, Lena, Vier, Juliane, Metz, Arlena, Eisele, Bianca, Bronsert, Peter, Aumann, Konrad, Höppner, Jens, Waguia Kontchou, Collins, Parui, Ishita, Weber, Arnim, Kirschnek, Susanne, Häcker, Georg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9613881/
https://www.ncbi.nlm.nih.gov/pubmed/35505004
http://dx.doi.org/10.1038/s41418-022-01009-9