Apoptotic priming is defined by the dynamic exchange of Bcl-2 proteins between mitochondria and cytosol

Apoptosis is regulated by interactions between the BH3-only and multi-domain Bcl-2 family proteins. These interactions are integrated on the outer mitochondrial membrane (OMM) where they set the threshold for apoptosis, known as mitochondrial priming. However, how mitochondrial priming is controlled...

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Detalles Bibliográficos
Autores principales: King, Louise E., Rodriguez-Enriquez, Ricardo, Pedley, Robert, Mellor, Charlotte E. L., Wang, Pengbo, Zindy, Egor, White, Michael R. H., Brennan, Keith, Gilmore, Andrew P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9613888/
https://www.ncbi.nlm.nih.gov/pubmed/35585181
http://dx.doi.org/10.1038/s41418-022-01013-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9613888/
https://www.ncbi.nlm.nih.gov/pubmed/35585181
http://dx.doi.org/10.1038/s41418-022-01013-z

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