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Apoptotic priming is defined by the dynamic exchange of Bcl-2 proteins between mitochondria and cytosol
Apoptosis is regulated by interactions between the BH3-only and multi-domain Bcl-2 family proteins. These interactions are integrated on the outer mitochondrial membrane (OMM) where they set the threshold for apoptosis, known as mitochondrial priming. However, how mitochondrial priming is controlled...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9613888/ https://www.ncbi.nlm.nih.gov/pubmed/35585181 http://dx.doi.org/10.1038/s41418-022-01013-z |