IK(Ca) channels control breast cancer metabolism including AMPK-driven autophagy

Ca(2+)-activated K(+) channels of intermediate conductance (IK) are frequently overexpressed in breast cancer (BC) cells, while IK channel depletion reduces BC cell proliferation and tumorigenesis. This raises the question, of whether and mechanistically how IK activity interferes with the metabolic...

Descripción completa

Detalles Bibliográficos
Autores principales: Gross, Dominic, Bischof, Helmut, Maier, Selina, Sporbeck, Katharina, Birkenfeld, Andreas L., Malli, Roland, Ruth, Peter, Proikas-Cezanne, Tassula, Lukowski, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9613901/
https://www.ncbi.nlm.nih.gov/pubmed/36302750
http://dx.doi.org/10.1038/s41419-022-05329-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9613901/
https://www.ncbi.nlm.nih.gov/pubmed/36302750
http://dx.doi.org/10.1038/s41419-022-05329-z

Ejemplares similares