Cryo-EM structure of an ATTRwt amyloid fibril from systemic non-hereditary transthyretin amyloidosis

Wild type transthyretin-derived amyloid (ATTRwt) is the major component of non-hereditary transthyretin amyloidosis. Its accumulation in the heart of elderly patients is life threatening. A variety of genetic variants of transthyretin can lead to hereditary transthyretin amyloidosis, which shows dif...

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Detalles Bibliográficos
Autores principales: Steinebrei, Maximilian, Gottwald, Juliane, Baur, Julian, Röcken, Christoph, Hegenbart, Ute, Schönland, Stefan, Schmidt, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9613903/
https://www.ncbi.nlm.nih.gov/pubmed/36302762
http://dx.doi.org/10.1038/s41467-022-33591-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9613903/
https://www.ncbi.nlm.nih.gov/pubmed/36302762
http://dx.doi.org/10.1038/s41467-022-33591-4

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