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Silk scaffolding drives self-assembly of functional and mature human brain organoids

Human pluripotent stem cells (hPSCs) are intrinsically able to self-organize into cerebral organoids that mimic features of developing human brain tissue. These three-dimensional structures provide a unique opportunity to generate cytoarchitecture and cell-cell interactions reminiscent of human brai...

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Detalles Bibliográficos
Autores principales: Sozzi, Edoardo, Kajtez, Janko, Bruzelius, Andreas, Wesseler, Milan Finn, Nilsson, Fredrik, Birtele, Marcella, Larsen, Niels B., Ottosson, Daniella Rylander, Storm, Petter, Parmar, Malin, Fiorenzano, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9614032/
https://www.ncbi.nlm.nih.gov/pubmed/36313550
http://dx.doi.org/10.3389/fcell.2022.1023279