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LXR agonist inhibits inflammation through regulating MyD88 mRNA alternative splicing

Liver X receptors (LXRs) are important regulators of cholesterol metabolism and inflammatory responses. LXR agonists exhibit potently anti-inflammatory effects in macrophages, which make them beneficial to anti-atherogenic therapy. In addition to transrepressive regulation by SUMOylation, LXRs can i...

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Detalles Bibliográficos
Autores principales: Li, Ni, Li, Yan, Han, Xiaowan, Zhang, Jing, Han, Jiangxue, Jiang, Xinhai, Wang, Weizhi, Xu, Yang, Xu, Yanni, Fu, Yu, Si, Shuyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9614042/
https://www.ncbi.nlm.nih.gov/pubmed/36313296
http://dx.doi.org/10.3389/fphar.2022.973612