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Beneficial effects of neuronal ATF6 activation in permanent ischemic stroke

Objective: Brain ischemia leads to the accumulation of unfolded/misfolded proteins in the endoplasmic reticulum (ER) lumen and consequently, ER stress. To help cells restore ER function, a series of adaptive stress response pathways, collectively termed the unfolded protein response (UPR), are activ...

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Detalles Bibliográficos
Autores principales: Li, Xuan, Li, Ran, Lu, Liping, Dhar, Ashis, Sheng, Huaxin, Yang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9614111/
https://www.ncbi.nlm.nih.gov/pubmed/36313623
http://dx.doi.org/10.3389/fncel.2022.1016391