Inhibition of inflammatory liver injury by the HMGB1-A box through HMGB1/TLR-4/NF-κB signaling in an acute liver failure mouse model

We aimed to investigate the preventive effect of high mobility group box 1 (HMGB1)-A box and the mechanism by which it alleviates inflammatory injury in acute liver failure (ALF) by inhibiting the extracellular release of HMGB1. BALB/c mice were intraperitoneally (i.p.) administered LPS/D-GalN to es...

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Detalles Bibliográficos
Autores principales: Luo, Lidan, Wang, Shuai, Chen, Bohao, Zhong, Mei, Du, Ruili, Wei, ChunShan, Huang, Furong, Kou, Xinhui, Xing, Yufeng, Tong, Guangdong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9614247/
https://www.ncbi.nlm.nih.gov/pubmed/36313316
http://dx.doi.org/10.3389/fphar.2022.990087

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9614247/
https://www.ncbi.nlm.nih.gov/pubmed/36313316
http://dx.doi.org/10.3389/fphar.2022.990087

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