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Group 1 metabotropic glutamate receptor 5 is involved in synaptically-induced Ca(2+)-spikes and cell death in cultured rat hippocampal neurons

Group 1 metabotropic glutamate receptors (mGluRs) can positively affect postsynaptic neuronal excitability and epileptogenesis. The objective of the present study was to determine whether group 1 mGluRs might be involved in synaptically-induced intracellular free Ca(2+) concentration ([Ca(2+)](i)) s...

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Detalles Bibliográficos
Autores principales: Yang, Ji Seon, Jeon, Sujeong, Jang, Hyun-Jong, Yoon, Shin Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Physiological Society and The Korean Society of Pharmacology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9614404/
https://www.ncbi.nlm.nih.gov/pubmed/36302627
http://dx.doi.org/10.4196/kjpp.2022.26.6.531