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Delivery strategies for CRISPR/Cas genome editing tool for retinal dystrophies: challenges and opportunities

CRISPR/Cas, an adaptive immune system in bacteria, has been adopted as an efficient and precise tool for site-specific gene editing with potential therapeutic opportunities. It has been explored for a variety of applications, including gene modulation, epigenome editing, diagnosis, mRNA editing, etc...

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Detalles Bibliográficos
Autores principales: Lohia, Aayushi, Sahel, Deepak Kumar, Salman, Mohd, Singh, Vivek, Mariappan, Indumathi, Mittal, Anupama, Chitkara, Deepak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shenyang Pharmaceutical University 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9614410/
https://www.ncbi.nlm.nih.gov/pubmed/36320315
http://dx.doi.org/10.1016/j.ajps.2022.02.001