Persistent DNA damage and oncogenic stress-induced Trem1 promotes leukemia in mice

The immune receptor TREM1 (Triggering receptor expressed on myeloid cells 1) is a master regulator of inflammatory response. Compelling evidence suggests important pathological roles for TREM1 in various types of solid tumors. However, the role of TREM1 in hematologic malignancies is not known. Our...

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Detalles Bibliográficos
Autores principales: Li, Xue, Chatla, Srinivas, Wilson, Andrew F., Wu, Limei, Atale, Neha, Du, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2022
Materias:
Article - Acute Myeloid Leukemia
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9614537/
https://www.ncbi.nlm.nih.gov/pubmed/35443564
http://dx.doi.org/10.3324/haematol.2021.280404

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9614537/
https://www.ncbi.nlm.nih.gov/pubmed/35443564
http://dx.doi.org/10.3324/haematol.2021.280404

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