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The NADPH oxidase NOX2 is a marker of adverse prognosis involved in chemoresistance of acute myeloid leukemias

Resistance to chemotherapeutic drugs is a major cause of treatment failure in acute myeloid leukemias (AML). To better characterize the mechanisms of chemoresistance, we first identified genes whose expression is dysregulated in AML cells resistant to daunorubicin or cytarabine, the main drugs used...

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Detalles Bibliográficos
Autores principales: Paolillo, Rosa, Boulanger, Mathias, Gâtel, Pierre, Gabellier, Ludovic, De Toledo, Marion, Tempé, Denis, Hallal, Rawan, Akl, Dana, Moreaux, Jérôme, Baik, Hayeon, Gueret, Elise, Recher, Christian, Sarry, Jean-Emmanuel, Cartron, Guillaume, Piechaczyk, Marc, Bossis, Guillaume
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9614539/
https://www.ncbi.nlm.nih.gov/pubmed/35172562
http://dx.doi.org/10.3324/haematol.2021.279889