Antibody-drug conjugates targeting TROP-2: Clinical development in metastatic breast cancer

Antibody drug conjugates (ADCs) combine the potent cytotoxicity of chemotherapy with the antigen -specific targeted approach of antibodies into one single molecule. Trophoblast cell surface antigen 2 (TROP-2) is a transmembrane glycoprotein involved in calcium signal transduction and is expressed in...

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Detalles Bibliográficos
Autores principales: Shastry, Mythili, Jacob, Saya, Rugo, Hope S., Hamilton, Erika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article(s) from the Special Issue on: Antibody-drug Conjugates; Edited by Giuseppe Curigliano, Hope Rugo
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9614644/
https://www.ncbi.nlm.nih.gov/pubmed/36302269
http://dx.doi.org/10.1016/j.breast.2022.10.007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9614644/
https://www.ncbi.nlm.nih.gov/pubmed/36302269
http://dx.doi.org/10.1016/j.breast.2022.10.007

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