Palmitate impairs circadian transcriptomics in muscle cells through histone modification of enhancers

Obesity and elevated circulating lipids may impair metabolism by disrupting the molecular circadian clock. We tested the hypothesis that lipid overload may interact with the circadian clock and alter the rhythmicity of gene expression through epigenomic mechanisms in skeletal muscle. Palmitate repro...

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Detalles Bibliográficos
Autores principales: Pillon, Nicolas J, Sardón Puig, Laura, Altıntaş, Ali, Kamble, Prasad G, Casaní-Galdón, Salvador, Gabriel, Brendan M, Barrès, Romain, Conesa, Ana, Chibalin, Alexander V, Näslund, Erik, Krook, Anna, Zierath, Juleen R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9614702/
https://www.ncbi.nlm.nih.gov/pubmed/36302651
http://dx.doi.org/10.26508/lsa.202201598

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9614702/
https://www.ncbi.nlm.nih.gov/pubmed/36302651
http://dx.doi.org/10.26508/lsa.202201598

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