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PDE12 in type 1 diabetes

Type 1 diabetes (T1D) incidence is increased after COVID-19 infection in children under 18 years of age. Interferon-α-activated oligoadenylate synthetase and downstream RNAseL activation degrade pathogen RNA, but can also damage host RNA when RNAseL activity is poorly regulated. One such regulator i...

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Detalles Bibliográficos
Autores principales: Tekin, Hasim, Josefsen, Knud, Krogvold, Lars, Dahl-Jørgensen, Knut, Gerling, Ivan, Pociot, Flemming, Buschard, Karsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9614732/
https://www.ncbi.nlm.nih.gov/pubmed/36307540
http://dx.doi.org/10.1038/s41598-022-22890-x