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Identification of tumor-associated antigens and immune subtypes of lower-grade glioma and glioblastoma for mRNA vaccine development

BACKGROUND: mRNA became a promising therapeutic approach in many diseases. This study aimed to identify the tumor antigens specifically expressed in tumor cells for lower-grade glioma (LGG) and glioblastoma (GBM) patients. METHODS: In this work, the mRNA microarray expression profile and clinical da...

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Detalles Bibliográficos
Autores principales: Wang, Zhi-liang, Huang, Ruo-yu, Han, Bo, Wu, Fan, Sun, Zhi-yan, Li, Guan-zhang, Zhang, Wei, Zhao, Zheng, Liu, Xing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9614757/
https://www.ncbi.nlm.nih.gov/pubmed/36307882
http://dx.doi.org/10.1186/s41016-022-00301-4