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Miro GTPase domains regulate the assembly of the mitochondrial motor–adaptor complex

Mitochondrial transport relies on a motor–adaptor complex containing Miro1, a mitochondrial outer membrane protein with two GTPase domains, and TRAK1/2, kinesin-1, and dynein. Using a peroxisome-directed Miro1, we quantified the ability of GTPase mutations to influence the peroxisomal recruitment of...

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Detalles Bibliográficos
Autores principales: Davis, Kayla, Basu, Himanish, Izquierdo-Villalba, Ismael, Shurberg, Ethan, Schwarz, Thomas L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9615026/
https://www.ncbi.nlm.nih.gov/pubmed/36302649
http://dx.doi.org/10.26508/lsa.202201406