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Direct Identification of Proteolytic Cleavages on Living Cells Using a Glycan-Tethered Peptide Ligase

[Image: see text] Proteolytic cleavage of cell surface proteins triggers critical processes including cell–cell interactions, receptor activation, and shedding of signaling proteins. Consequently, dysregulated extracellular proteases contribute to malignant cell phenotypes including most cancers. To...

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Detalles Bibliográficos
Autores principales: Schaefer, Kaitlin, Lui, Irene, Byrnes, James R., Kang, Emily, Zhou, Jie, Weeks, Amy M., Wells, James A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9615116/
https://www.ncbi.nlm.nih.gov/pubmed/36313159
http://dx.doi.org/10.1021/acscentsci.2c00899