Exploring the druggability of the binding site of aurovertin, an exogenous allosteric inhibitor of F(O)F(1)-ATP synthase

In addition to playing a central role in the mitochondria as the main producer of ATP, F(O)F(1)-ATP synthase performs diverse key regulatory functions in the cell membrane. Its malfunction has been linked to a growing number of human diseases, including hypertension, atherosclerosis, cancer, and som...

Descripción completa

Detalles Bibliográficos
Autores principales: Cofas-Vargas, Luis Fernando, Mendoza-Espinosa, Paola, Avila-Barrientos, Luis Pablo, Prada-Gracia, Diego, Riveros-Rosas, Héctor, García-Hernández, Enrique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9615146/
https://www.ncbi.nlm.nih.gov/pubmed/36313289
http://dx.doi.org/10.3389/fphar.2022.1012008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9615146/
https://www.ncbi.nlm.nih.gov/pubmed/36313289
http://dx.doi.org/10.3389/fphar.2022.1012008

Ejemplares similares