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Exploring the druggability of the binding site of aurovertin, an exogenous allosteric inhibitor of F(O)F(1)-ATP synthase

In addition to playing a central role in the mitochondria as the main producer of ATP, F(O)F(1)-ATP synthase performs diverse key regulatory functions in the cell membrane. Its malfunction has been linked to a growing number of human diseases, including hypertension, atherosclerosis, cancer, and som...

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Detalles Bibliográficos
Autores principales:	Cofas-Vargas, Luis Fernando, Mendoza-Espinosa, Paola, Avila-Barrientos, Luis Pablo, Prada-Gracia, Diego, Riveros-Rosas, Héctor, García-Hernández, Enrique
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9615146/ https://www.ncbi.nlm.nih.gov/pubmed/36313289 http://dx.doi.org/10.3389/fphar.2022.1012008

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