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Translational alterations in pancreatic cancer: a central role for the integrated stress response

mRNA translation is a key mechanism for cancer cell proliferation and stress adaptation. Regulation of this machinery implicates upstream pathways such as PI3K/AKT/mTOR, RAS/MEK/ERK and the integrated stress response (ISR), principally coordinating the translation initiation step. During the last de...

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Detalles Bibliográficos
Autores principales: Shin, Sauyeun, Solorzano, Jacobo, Liauzun, Mehdi, Pyronnet, Stéphane, Bousquet, Corinne, Martineau, Yvan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9615149/
https://www.ncbi.nlm.nih.gov/pubmed/36325577
http://dx.doi.org/10.1093/narcan/zcac031